Anti-Inflammatory and Immunomodulatory Properties of Natural Products

Inflammation and immune system activation are central body pathways that work in concert as a vital defense mechanism against harmful stimuli like pathogens, damaged cells, and toxic compounds. They are essential for maintaining health and initiating the healing process. However, prolonged inflammation and immune system activation are indeed dangerous, as it can damage healthy cells and tissues and are linked to numerous chronic diseases. Natural compounds are promising agents that exhibit inflammation and immunomodulatory properties. Natural products have been extensively applied against various inflammatory and immune system disorders, i.e., rheumatoid arthritis, inflammatory bowel diseases, and plague psoriasis. The current chapter discusses the importance of different natural products (flavonoids, alkaloids, terpenes and terpenoids, curcumin, and andrographolide) in the regulation of inflammatory and immune system response. Moreover, the different pathways that are targeted by natural products against these disorders are also discussed in this chapter. Furthermore, this chapter emphasizes future research on the safety and effectiveness of natural products against these inflammatory and immune system disorders.