Natural Compounds in Metabolic Disorders: Diabetes, Obesity and Cardiovascular Diseases

This chapter provides an overview of research into the efficacy of natural substances for the management of obesity, diabetes, and cardiovascular diseases (CVDs). The pathogenesis of these disorders is almost similar and includes oxidative damage, inflammation, and insulin resistance. The study claims that alkaloids and polyphenols, two anti-diabetic substances, boost insulin activity while preserving blood glucose stability. Moreover, the current chapter examines the impact of anti-obesity drugs on gut flora and lipid metabolism, with a focus on flavonoids and diets high in fiber. Furthermore, this chapter assesses the cardioprotective advantages of carotenoids and polyphenols by looking at their anti-inflammatory and antioxidant properties. Additionally, a summary of clinical trials, present barriers to bioavailability improvement and standardization are also provided. Moreover, this chapter proposes future directions for the application of natural compounds in personalized medical care.